While by far not an exclusive list of the articles outlining the rapid growth and progress made in the field of metabolomics, this selection of articles represents a good mixture of both technological reviews and creative studies in which metabolite analysis was used...

• Want EJ, Nordstrom A, Morita H, Siuzdak G
  From Exogenous to Endogenous: The Inevitable Imprint of Mass Spectrometry in Metabolomics
  Journal of Proteome Research, 2007, 6(2), 459-468

• Dettmer K, Aronov PA, Hammock BD
  Mass spectrometry-based metabolomics
  Mass Spectrom Rev., 2007, 26(1), 51-78

• Doerr A
  Annotating the unannotated.
  Nat Methods., 2007, 4(1), 8-9

• Wishart DS, Tzur D, Knox C, Eisner R, Guo AC, Young N, Cheng D, Jewell K, Arndt D, Sawhney S, Fung C, Nikolai L, Lewis M, Coutouly MA, Forsythe I, Tang P, Shrivastava S, Jeroncic K, Stothard P, Amegbey G, Block D, Hau DD, Wagner J, Miniaci J, Clements M,
  HMDB: the Human Metabolome Database
  Nucleic Acids Res., 2007, 35, D521-6

• Pietilainen KH, Sysi-Aho M, Rissanen A, Seppanen-Laakso T, Yki-Jarvinen H, Kaprio J, Oresic M
  Acquired Obesity Is Associated with Changes in the Serum Lipidomic Profile Independent of Genetic Effects - A Monozygotic Twin Study
  Plos One, 2007, 2(e218), 1-14

• Smith CA, Want EJ, O'Maille G, Abagyan R, Siuzdak G
  XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching and identification
  Analytical Chemistry, 2006, 78, 779-787

• Salek RM, Maguire ML, Bentley E, Rubtsov DV, Hough T, Cheeseman M, Nunez DJ, Sweatman BC, Haselden JN, Cox R, Connor SC, Griffin JL
  A Metabolomic Comparison of Urinary Changes in Type 2 Diabetes in Mouse, Rat and Man
  Physiol Genomics., 2006, , 26

• Stella C, Beckwith-Hall B, Cloarec O, Holmes E, Lindon JC, Powell J, van der Ouderaa F, Bingham S, Cross AJ, Nicholson JK
  Susceptibility of human metabolic phenotypes to dietary modulation
  J Proteome Res., 2006, 5(10), 2780-8

• Griffin JL
  Understanding mouse models of disease through metabolomics
  Curr Opin Chem Biol., 2006, 10(4), 309-15

• Teahan O, Gamble S, Holmes E, Waxman J, Nicholson JK, Bevan C, Keun HC
  Impact of analytical bias in metabonomic studies of human blood serum and plasma
  Anal Chem., 2006, 78(13), 4307-18

• Fiehn O, Kristal B, van Ommen B, Sumner LW, Sansone SA, Taylor C, Hardy N, Kaddurah-Daouk R
  Establishing reporting standards for metabolomic and metabonomic studies: a call for participation
  OMICS., 2006, 10(2), 158-63

• Mendes P
  Metabolomics and the challenges ahead
  Brief Bioinform., 2006, 7(2), 127

• Castle AL, Fiehn O, Kaddurah-Daouk R, Lindon JC
  Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results
  Brief Bioinform., 2006, 7(2), 159-65

• Kind T, Fiehn O
  Metabolomic database annotations via query of elemental compositions: mass accuracy is insufficient even at less than 1 ppm
  BMC Bioinformatics, 2006, 28(7), 234

• Rischer H, Oksman-Caldentey KM
  Unintended effects in genetically modified crops: revealed by metabolomics?
  Trends Biotechnol., 2006, 24(3), 102-4

• Plumb RS, Johnson KA, Rainville P, Shockcor JP, Williams R, Granger JH, Wilson ID
  The detection of phenotypic differences in the metabolic plasma profile of three strains of Zucker rats at 20 weeks of age using ultra-performance liquid chromatography/orthogonal acceleration time-of-flight mass spectrometry
  Rapid Commun Mass Spectrom., 2006, 20(19), 2800-6

• Smith CA, O'Maille G, Want EJ, Qin C, Trauger SA, Brandon TR, Custodio DE, Abagyan R, Siuzdak G
  METLIN: A Metabolite Mass Spectral Database
  Therapeutic Drug Monitoring, 2005, 27(6), 747-751

• Brown SC, Kruppa G, Dasseux JL
  Metabolomics applications of FT-ICR mass spectrometry
  Mass Spectrom Rev., 2005, 24(2), 223-31

• Catchpole GS, Beckmann M, Enot DP, Mondhe M, Zywicki B, Taylor J, Hardy N, Smith A, King RD, Kell DB, Fiehn O, Draper J
  Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops
  Proc Natl Acad Sci U S A, 2005, 102(40), 14458-62

• Gibney MJ, Walsh M, Brennan L, Roche HM, German B, van Ommen B
  Metabolomics in human nutrition: opportunities and challenges
  Am J Clin Nutr., 2005, 82(3), 497-503

• Morris M, Watkins SM
  Focused metabolomic profiling in the drug development process: advances from lipid profiling
  Curr Opin Chem Biol., 2005, 9(4), 407-12

• Ippolito JE, Xu J, Jain S, Moulder K, Mennerick S, Crowley JR, Townsend RR, Gordon JI
  An integrated functional genomics and metabolomics approach for defining poor prognosis in human neuroendocrine cancers
  Proc Natl Acad Sci., 2005, 102(28), 9901-6

• Jonsson P, Gullberg J, Nordstrom A, Kusano M, Kowalczyk M, Sjostrom M, Moritz T.
  A strategy for identifying differences in large series of metabolomic samples analyzed by GC/MS
  Anal Chem., 2004, 76(6), 1738-45

• Jenkins H, Hardy N, Beckmann M, Draper J, Smith AR, Taylor J, Fiehn O, Goodacre R, Bino RJ, Hall R, Kopka J, Lane GA, Lange BM, Liu JR, Mendes P, Nikolau BJ, Oliver SG, Paton NW, Rhee S, Roessner-Tunali U, Saito K, Smedsgaard J, Sumner LW, Wang T, Walsh S
  A proposed framework for the description of plant metabolomics experiments and their results
  Nat Biotechnol., 2004, 22(12), 1601-6

• Griffin JL
  Metabolic profiles to define the genome: can we hear the phenotypes?
  Philos Trans R Soc Lond B Biol Sci., 2004, 359(1446), 857-71

• German JB, Bauman DE, Burrin DG, Failla ML, Freake HC, King JC, Klein S, Milner JA, Pelto GH, Rasmussen KM, Zeisel SH
  Metabolomics in the opening decade of the 21st century: building the roads to individualized health
  J Nutr., 2004, 134(10), 2729-32

• Coen M, Ruepp SU, Lindon JC, Nicholson JK, Pognan F, Lenz EM, Wilson ID
  Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse
  J Pharm Biomed Anal., 2004, 35(1), 93-105

• Hirai MY, Yano M, Goodenowe DB, Kanaya S, Kimura T, Awazuhara M, Arita M, Fujiwara T, Saito K
  Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana
  Proc Natl Acad Sci, 2004, 101(27), 10205-10

• Mendes P.
  Emerging bioinformatics for the metabolome
  Brief Bioinform., 2002, 3(2), 134-45

• Fiehn O
  Metabolomics--the link between genotypes and phenotypes
  Plant Mol Biol., 2002, 48(1-2), 155-71

• Brindle JT, Antti H, Holmes E, Tranter G, Nicholson JK, Bethell HW, Clarke S, Schofield PM, McKilligin E, Mosedale DE, Grainger DJ
  Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
  Nat Med., 2002, 8(12), 1439-44

• Watkins SM, Reifsnyder PR, Pan HJ, German JB, Leiter EH
  Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone
  J Lipid Res., 2002, 43(11), 1809-17

• Raamsdonk LM, Teusink B, Broadhurst D, Zhang N, Hayes A, Walsh MC, Berden JA, Brindle KM, Kell DB, Rowland JJ, Westerhoff HV, van Dam K, Oliver SG
  A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
  Nat Biotechnol., 2001, 19(1), 45-50

• Fiehn O, Kopka J, Dormann P, Altmann T, Trethewey RN, Willmitzer L.
  Metabolite profiling for plant functional genomics
  Nat Biotechnol., 2000, 18(11), 1157-61

• Nicholson JK, Lindon JC, Holmes E
  Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
  Xenobiotica, 1999, 29(11), 1181-9

• Millington DS, Kodo N, Norwood DL, Roe CR
  Tandem Mass Spectrometry: A New Method for Acylcarnitine Profiling with Potential for Neonatal Screening for Inborn Errors of Metabolism
  J. Inher. Metab. Dis., 1990, 13, 321-324