1957

First Knudsen cell/mass spectrometer system for high temperature thermodynamics research/ NUCLIDE ASSOCIATES (State College, PA).

1958

First GC/MS assembled by Roland Gohlke and Fred McLafferty at DOW CHEMICAL RESEARCH LABORATORY in Midland, MI, using a Model 12-101 Time-of-Flight mass spectrometer by Bendix Corp. Direct coupling of GC effluent using a needle valve.

1959

Multiple ion monitoring invented on TOF mass spectrometer by Donald Damoth of BENDIX RESEARCH LABORATORY

Solids inlet probe on mass spectrometer invented by Donald Damoth of BENDIX RESEARCH LABORATORY. Used for first MS confirmation of molecular weight of cholesterol for Dr. Djerassi of Wayne State University.

1960

First mass spectrometer with solids injection probe sold to UNITED STATES PUBLIC HEALTH SERVICE LABORATORIES in Cincinnati, OH. Used by Dr. Richard Kupel to study the decomposition of Teflon.

1962

Total ion monitoring invented by Donald Damoth and Roland Gohlke for GC/MS.

1963

First commercial Quadrupole mass spectrometer sold by ELECTRONICS ASSOCIATES, INC. to NASA as residual gas analyzer for space chamber research.

First Magnetic Sector mass spectrometer sold by HITACHI for GC/MS research.

1964

GC/MS designed and built by Ragnar Ryhage of the KAROLINSKA INSTITUTE in Stockholm, Sweden.

1965

First pre-packaged Magnetic Sector mass spectrometer with Helium enrichment jet separator by Ragnar Ryhage of the Karolinska Institute, sold by LKB INSTRUMENTS.

1967

Robert Finnigan leaves EAI to start FINNIGAN INSTRUMENTS and commercializes Quadrupole GC/MS.

PERKIN ELMER introduces first magnetic double focusing GC/MS, Model 270.