1985 - Matrix-Assisted Laser Desorption Ionization (MALDI)

MALDI (along with electrospray) was one of the most important discoveries in mass spectrometry in the latter part of the twentieth century.

• Karas M., Bachmann D., Hillenkamp F.
  Influence of the Wavelength in High Irradiance Ultraviolet Laser Desorption Mass Spectrometry of Organic Molecules
  Anal. Chem., 1985, 57(), p.2935-2939

  
  
  

• Tanaka K., Ido Y., Akita S., Yoshida Y., Yoshida T.
  Detection of High Mass Molecules by Laser Desorption Time-Of-Flight Mass Spectrometry
  Proceedings of the Second Japan-China Joint Symposium on Mass Spectrometry, 1987, (), p.185

  
  
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• Tanaka K., Waki H., Ido Y., Akita S., Yoshida Y., Yoshida T.
  Protein and polymer analysis up to m/z 100,000 by laser ionization time-of-flight mass spectrometry
  Rapid Commun. Mass Spectrom., 1988, 2(8), p.151

  
  
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• Karas M., Hillenkamp F.
  Laser desorption ionization of proteins with molecular mass exceeding 10,000 Daltons
  Analytical Chemistry, 1988, 60(), p.2299

  
  
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• Karas M., Hillenkamp F.
  Laser Desorption Ionization of Proteins with Molecular Masses Exceeding 10,000 Daltons
  Anal. Chem., 1988, 60(20), p.2299-2301