Contribution

Year

• Early Mass Spectrometry

• 1897

• The observation of isotopes using mass spectrometry

• 1919

• Double Focusing Analyzer

• 1934

• Time-of-Flight Mass Spectrometry

• 1946

• Preparative Mass Spectrometry

• 1947

• Ion Cyclotron Resonance (ICR)

• 1949

• Reverse Geometry Double-Focusing MS

• 1953

• Quadrupole Analyzers

• 1953

• Gas Chromatography Mass Spectrometry (GC/MS)

• 1956

• Identifying Organic Compounds with Mass Spectrometry

• 1956

• Mass Spectrometry Imaging

• 1962

• Chemical Ionization

• 1966

• Peptide Sequencing

• 1966

• Tandem Mass Spectrometry

• 1966

• Metabolomics

• 1966

• Electrospray Ionization

• 1968

• Collision Induced Dissociation

• 1968

• Field Desorption-MS of Organic Molecule

• 1969

• Fourier Transform Ion Cyclotron Resonance

• 1974

• Extra-Terrestrial Mass Spectrometry

• 1974

• Atmospheric Pressure Chemical Ionization (APCI)

• 1975

• Californium-252 Plasma Desorption MS

• 1976

• Accelerator Mass Spectrometry

• 1977

• GC-C-IRMS

• 1978

• Triple Quadrupole Mass Analyzer

• 1978

• Inductively Coupled Plasma MS

• 1980

• Matrix-Assisted Desorption Ionization

• 1981

• Quadrupole/Time-Of-Flight Mass Analyzer

• 1984

• Matrix-Assisted Laser Desorption Ionization (MALDI)

• 1985

• Soft Laser Desorption of Proteins

• 1987

• ESI on Biomolecules

• 1989

• Monitoring Enzyme Reactions with ESI-MS

• 1989

• Protein Conformational Changes with ESI-MS

• 1990

• Clinical Mass Spectrometry

• 1990

• MALDI Post-Source Decay

• 1991

• Non-covalent Interactions with ESI

• 1991

• Low Level Peptide Analysis

• 1992

• Oligonucleotide Ladder Sequencing

• 1993

• Protein Mass Mapping

• 1993

• Intact Virus Analyses

• 1996

• Electron Capture Dissociation (ECD)

• 1998

• Nanostructure Desorption/Ionization

• 1999

• Quantitative Proteomics and Metabolomics with Isotope Labels

• 1999

• Orbitrap

• 2000

• Desorption Electrospray Ionization (DESI)

• 2004

• Electron Transfer Dissociation (ETD)

• 2004

• Direct Analysis in Real Time (DART)

• 2005