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Our interests focus on biomolecule characterization (both structure and activity) through the development of novel and existing mass spectrometry technology.
Our findings include:
- Mass analysis of intact viruses -
pdf1,
pdf2
- Preparative MS with Electrospray -
pdf3
- Mass-based inhibitor-enzyme screen -
pdf4,
pdf5
- Observation of viral capsid dynamics -
pdf6,
pdf7,
pdf8
- Desorption/Ionization on Silicon (DIOS) -
pdf9
- XCMS: a nonlinear approach to align LC/MS data -
pdf10
- Nanostructure Initiated Mass Spectrometry (NIMS)
| 146 |
Yanes O., Hsu J., Wong D.M., Sanchez-Ruiz A., Benton H.P., Trauger S.A., Despont C., Ding S., Siuzdak G.
Endogenous metabolites regulate stem cell differentiation
submitted, 2008, ,
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| 145 |
Benton H.P., Wong D.M., Siuzdak G.
XCMS2: Processing tandem mass spectrometry data for metabolite identification and structural characterization
Analytical Chemistry, in press, 2008, , Related Page
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| 144 |
Woo H-K., Northen T.R., Yanes O., Siuzdak G.
Nanostructure-Initiator Mass Spectrometry (NIMS): A protocol for preparing and applying NIMS surfaces for high sensitivity mass analysis
Nature Protocols, in press, 2008, ,
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| 143 |
Wikoff W.R., Pendyala G., Siuzdak G., Fox H.S.
CSF metabolome changes in SIV-infected monkeys reveal altered CNS phospholipase expression
Journal of Clinical Investigation, in press, 2008, ,
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| 142 |
Northen T.R., Lee J-C, Hoang L., Raymond J., Hwang D-R, Yannone S.M., Wong C-H, Siuzdak G.
A Nanostructure-Initiator Mass Spectrometry-Based Enzyme Activity Assay
PNAS, 2008, 105(10), 3678-3683 PDF File
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| 141 |
Nordstrom A. Want E., Northen T., Lehtio J., Siuzdak G.
Multiple Ionization Mass Spectrometry Strategy Reveals the Complexity of Metabolomics
Analytical Chemistry, 2008, 80, 421-429 PDF File
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| 140 |
Trauger S.A., Kalisiak E., Kalisiak J., Morita H., Weinbergb M.V., Menon A.L., Poole F.L. II, Adams M.W.W., Siuzdak G.
Correlating the Transcriptome, Proteome, and Metabolome in the Environmental Adaptation of a Hyperthermophile
Journal of Proteome Research, 2008, 7, 1027-1035 PDF File
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| 139 |
O'Maille G., Hoang L., Nordstrom A., Go E.P., Qin C., Siuzdak G.
Metabolomics Mass Spectrometry Profiling using Chemical Derivatization with Isotope Labeling
in press, 2008, ,
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| 138 |
Yanes O., Northen T.R., Uritboonthai W., Estrada M.N., Manchester M., Siuzdak G.
Nanostructure Initiator Mass Spectrometry for Biological Tissue Imaging and Biofluid Analysis
, submitted, 2008, ,
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| 137 |
Volker V., Eraly S.A., Wikoff W.R., Rieg T., Kaler G., Truong D.M., Ahn S-A., Mhapatra N.R., Mahata S.K., Gangoiti J.A., Wu W., Barshop B.A., Siuzdak G., Nigam S.K.
Loss of Organic Anion Transporter 3 Results in Lowered Blood Pressure: Potential Role for Oat3 in the Transport of Endogenous Regulators of Blood Pressure
J. Am. Soc. of Nephrology, in press, 2008, ,
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| 136 |
Northen T.R., Yanes O., Northen M.T., Marrinucci D., Uritboonthai W., Apon J., Golledge S.L., Nordstrom A., Siuzdak G.
Clathrate Nanostructures for Mass Spectrometry
Nature, 2007, 449, 1033-1036
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| 135 |
Wikoff W.R., Gangoitti J.A., Barshop B.A., Siuzdak G.
Metabolomics Identifies Novel Perturbations in Human Disorders of Propionate Metabolism
Clinical Chemistry, 2007, 53, 2169-2176
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| 134 |
Go E.P., Uritboonthai W., Apon J.A., Trauger S.A., Nordstrom A., O'Maille G., Brittain S., Peters E.C., Siuzdak G.
Selective Metabolite and Peptide Capture/Mass Detection Using Fluorous Affinity Tags
Journal of Proteome Research, 2007, 6, 1492-1499 PDF File
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| 133 |
Cohen L., Go E.P. , Siuzdak G.
Small Molecule Desorption/Ionization Mass Analysis
MALDI-MS Franz Hillenkamp - editor, 2007, IX, 299 PDF File
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| 132 |
Nordstrom A., He L., Siuzdak G.
Desorption/Ionization on Silicon (DIOS)
Encyclopedia of Mass Spectrometry, Editor Michael Gross, 2007, 6, 676-683 PDF File
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| 131 |
Northen T.R., Woo H.K., Northen M.T., Nordstrom A., Uritboonthai W., Turner K., Siuzdak G.
High Surface Area of Porous Silicon Drives Desorption of Intact Molecules
J. Am. Soc. Mass Spectrom., 2007, 18(11), 1945-1949 PDF File
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| 130 |
Pendyala G., Want E.J., Webb W., Siuzdak G., Fox H.S.
Biomarkers for NeuroAIDS: The widening scope of Metabolomics
Journal of NeuroImmune Pharmacology, 2007, 2, 72-80 PDF File
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| 129 |
Want E.J., Nordstrom A., Morita H., Siuzdak G.
From Exogenous to Endogenous: The Inevitable Imprint of Mass Spectrometry in Metabolomics
Journal of Proteome Research, 2007, 6(2), 459-468 PDF File
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| 128 |
Northen T.R., Nordstrom A., Yanes O., Siuzdak G.
Nanostructure-Initiator Mass Spectrometry
patent application, 2007, ,
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| 127 |
Mutch D.M., O'Maille G., Wikoff W., Wiedmer T., Sims P.J., Siuzdak G.
Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice
Genome Biology, 2007, 8, R38 PDF File
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| 126 |
Chace D.H., Barr J.R., Duncan M.W., Matern D., Morris M.R., Palmer-Toy D.E., Rockwood A.L., Siuzdak G., Urbani A., Yergey A.L., Chan Y.M.
Mass Spectrometry in the Clinical Laboratory: General Principles and Guidance
Clinical and Laboratory Standards Institute, 2007, 27, 1-91
|
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| 125 |
Lissauer M., Johnson S.B., Siuzdak G., Bochicchio G., Whiteford C., Nussbaumer W., Moore R., Scalea T.S.
Coagulation and Complement Protein Differences Between Septic and Uninfected SIRS Patients
The Journal of Trauma, Injury, Infection and Critical Care, 2007, 62(5), 1080-1094 PDF File
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| 124 |
Nordstrom A., Apon J.V., Uritboonthai W., Go E.P., Siuzdak G.
Surfactant Enhanced Desorption/Ionization on Silicon (DIOS) Mass Spectrometry
Analytical Chemistry, 2006, 78, 272-278 PDF File
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| |
| 123 |
Want E.J., O'Maille G., Smith C.A., Brandon T.R., Uritboonthai W., Qin C., Trauger S.A., Siuzdak G.
Solvent-Dependent Metabolite Distribution, Clustering and Protein Extraction for Serum Profiling with Mass Spectrometry
Analytical Chemistry, 2006, 78, 743-752 PDF File
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| 122 |
Siuzdak G.
The Expanding Role of Mass Spectrometry in Biotechnology - 2nd Edition
MCC Press, San Diego, 2006, III, 1-252
|
| |
| 121 |
Smith C.A., Want E.J., O'Maille G., Abagyan R., Siuzdak G.
XCMS: Processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching and identification
Analytical Chemistry, 2006, 78, 779-787 PDF File
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| |
| 120 |
Want E.J., Smith C., Siuzdak G.
Phospholipid Capture Combined with Non-Linear Chromatographic Correction for Improved Metabolite Profiling
Metabolomics, 2006, 2, 145-154 PDF File
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| 119 |
Shen Z., Want E.J., Chen W., Keating W, Nussbaumer W, Moore R, Gentle T.M., Siuzdak G.
Sepsis Plasma Protein Profiling with Immunodepletion, Three-Dimensional Liquid Chromatography Tandem Mass Spectrometry and Spectrum Counting
Journal of Proteome Research, 2006, 5 (11), 3154 - 3160 PDF File
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| 118 |
Lee J-C.,Wu C-Y., Apon J.V., Siuzdak G., Wong C-H.
Reactivity-Based One-Pot Synthesis of Tumor-Associated Antigen N3 Minor Octasaccharide: A Case Study of DIOS-MS Sugar Array**
Angew Chem Int Ed, 2006, 45, 2753 - 2757 PDF File
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| 117 |
Go E.P., Wikoff W., Shen Z., O'Maille G., Morita H., Conrads T.P., Nordstrom A., Trauger S.A., Uritboonthai W., Lucas D., Chan K.C., Veenstra T.D., Lewicki H., Oldstone M.B., Schneemann A., Siuzdak G.
Mass Spectrometry Reveals Specific and Global Molecular Transformations during Viral Infection
Journal of Proteome Research, 2006, 5 (9), 2405 - 2416 PDF File
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| 116 |
Nordstrom A., O'Maille G., Qin C., Siuzdak G.
Non-linear Data Alignment for UPLC-MS and HPLC-MS based Metabolomics: Quantitative Analysis of Endogenous and Exogenous Metabolites in Human Serum
Analytical Chemistry, 2006, 78, 7289-3295 PDF File
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| 115 |
Steenwyk R., Hutzler J.M., Sams J., Shen Z., Siuzdak G.
Atmospheric Pressure Desorption/Ionization on Silicon Ion Trap Mass Spectrometry Applied to the Quantitation of Mdazolam in Plasma and Midazolam 1' - Hydroxylation Kinetics In Human Liver Microsomes
Rapid Communication in Mass Spectrometry, in press, 2006, 20, 3717-3722 PDF File
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| 114 |
Smith C.A., O'Maille G., Want E.J., Qin C., Trauger S.A., Brandon T.R., Custodio D.E., Abagyan R., Siuzdak G.
METLIN: A Metabolite Mass Spectral Database
Therapeutic Drug Monitoring, 2005, 27(6), 747-751 PDF File
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| 113 |
Lowe R., G E., Tong G., Voelcker N.H., Siuzdak G.
Monitoring EDTA and endogenous metabolite from serum with mass spectrometry
Spectroscopy, 2005, 19(13), 137-146 PDF File
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| |
| 112 |
Lacy E.R., Wang Y., Post J., Nourse A., Webb W., Mapelli M., Musacchio A., Siuzdak G., Kriwacki R.
Molecular Basis for the Specificity of p27 Toward Cyclin-dependent Kinases that Regulate Cell Division
Journal of Molecular Biology, 2005, 349, 764-773
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| 111 |
Bothner B., Taylor D., Jun B., Lee K., Siuzdak G., Schultz C.P., Johnson J.
Maturation of a tetravirus capsids alters the dynamic properties and creates a metastable complex
Virology, 2005, 334, 17-27 PDF File
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| 110 |
Go E.P., Apon J.V., Luo G., Saghatelian A., Daniels R.H., Sahi V., Cravatt B., Vertes A., Dubrow R., Siuzdak G.
Desorption/Ionization of Silicon Nanowires
Analytical Chemistry, 2005, 77, 1641-6 PDF File
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| 109 |
Want E., Cravatt B.F., Siuzdak G.
The Expanding Role of Mass Spectrometry in Metabolite Profiling and Characterization
ChemBioChem, 2005, 6, 1941-1951 PDF File
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| 108 |
Talkington M.T., Siuzdak G., Williamson J.R.
An assembly landscape for the 30S ribosomal subunit
Nature, 2005, 438, 628-632 PDF File
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| 107 |
Luo G., Chen Y., Siuzdak G., Vertes A.
Surface Modification and Laser Pulse Length Effects on Internal Energy Transfer in DIOS
Journal of Physical Chemistry B, 2005, 109, 24450-24456 PDF File
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| 106 |
Siuzdak G.
An Introduction to Mass Spectrometry Ionization
Journal of the Association of Lab Automation, 2004, 9(2), 50-63 PDF File
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| 105 |
Shen Z., Thomas J.J., Siuzdak G., Blackledge R.D.
A Case Study on Forensic Polymer Analysis by DIOS-MS
Journal of Forensic Science, 2004, 49, 1-8 PDF File
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| 104 |
Meng J.-C., Siuzdak G., Finn M.G.
Affinity Mass Spectrometry from a Tailored Porous Silicon Surface
Chemical Communications, 2004, 18, 2108-2109 PDF File
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| |
| 103 |
Kriwacki R., Reisdorph N., Siuzdak G.
Protein Structure Characterization with Mass Spectrometry
Spectroscopy, 2004, 18, 37-47 PDF File
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| 102 |
Wu, E., Trauger, S.A., Pache, L., Mullen, T.-M., Von Seggern, D.J., Siuzdak, G., Nemerow, G.R.
Membrane Cofactor Protein (MCP: CD46) is a Receptor for Adenoviruses Associated with Epidemic Keratoconjunctivitis
Journal of Virology, 2004, 78, 3897-3905 PDF File
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| 101 |
Meng J.-C., Averbuj C., Siuzdak G., Finn M.G.
Cleavable Linkers for Porous Silicon-Based Mass Spectrometry
Angewandte Chemie, 2004, 43, 1255-1260 PDF File
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| 100 |
Bothner B., Siuzdak G.
Electrospray Ionization of a Whole Virus: Analyzing Mass, Structure and Viability
ChemBioChem, 2004, 5(3), 258-260 PDF File
|
| |
| 99 |
Shen Z., Go E.P., Gamez A., Apon J.V., Fokin V., Greig M., Ventura M., Crowell J.E., Blixt O., Paulson J.C., Stevens R., Finn M.G., Siuzdak G.
A Mass Spectrometry Plate Reader: Monitoring Enzyme and Inhibitor Activity with Desorption/Ionization on Silicon (DIOS) Mass Spectrometry
ChemBioChem, 2004, 5, 921-927 PDF File
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| |
| 98 |
Thomas J.J., Bothner B., Traina J., Benner W.H., Siuzdak G.
Electrospray Ion Mobility Spectrometry of Intact Viruses
Spectroscopy, 2004, 18, 31-36 PDF File
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| |
| 97 |
Trauger S., Go E.P., Shen Z., Apon J.V., Compton B., Bouvier E.S.P., Finn M.G., Siuzdak G.
High Sensitivity and Analyte Capture with Desorption/Ionization Mass Spectrometry on Silylated Silicon
Analytical Chemistry, 2004, 76, 4484-4489 PDF File
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| 96 |
Siuzdak G., Go E., Shen Z., Compton B., Bouvier E.
Methods, Compositions and Devices for Performing Ionization Desorption on Silicon Derivatives
patent application, 2004, ,
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| |
| 95 |
Trauger S.A., Wu E., Bark S.B., Nemerow G.R., Siuzdak G.
The Identification of a Unique Adenovirus Receptor Using Affinity-Capture and Mass Spectrometry
ChemBioChem, 2004, 5(8), 1095-1099 PDF File
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| 94 |
Saghatelian A., Trauger S.A., Want E., Hawkins G., Siuzdak G., Cravatt B.F.
Assignment of Endogenous Substrates to Enzyme by Global Metabolite Profiling
Biochemistry, 2004, 43, 14332-14339 PDF File
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| 93 |
Want E.J., Greig M., Compton B.J., Bolaņos B., Siuzdak G.
Mass Spectrometry in High Throughput Analysis
Spectroscopy, 2003, 17, 663-680 PDF File
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| 92 |
Want E., Compton B.J., Hollenbeck T., Siuzdak G.
The Application of Mass Spectrometry in Pharmacokinetics
Spectroscopy, 2003, 17, 681-691 PDF File
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| 91 |
Siuzdak G.
The Expanding Role of Mass Spectrometry in Biotechnology
MCC Press: San Diego, 2003, ,
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| |
| 90 |
Prenni J.E., Shen Z., Trauger S., Chen W., Siuzdak G.
Protein Characterization using Liquid Chromatography Desorption Ionization on Silicon Mass Spectrometry (LC-DIOS-MS)
Spectroscopy, 2003, 17, 693-698 PDF File
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| 89 |
Compton B.J., Siuzdak G.
Mass Spectrometry in Nucleic Acid, Carbohydrate, and Steroid Analysis
Spectroscopy, 2003, 17, 699-713 PDF File
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| 88 |
Barker, G., Want, E., Boydston, J., Siuzdak, G.
Mass Spectrometry
Science of Synthesis/ Houben-Weyl, 2003, 7.6, 680-695 PDF File
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| 87 |
Lewis W., Shen Z., Finn M.G., Siuzdak G.
Desorption/ionization on silicon (DIOS) mass spectrometry: background and applications
International Journal of Mass Spectrometry, 2003, 226, 107-116 PDF File
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| |
| 86 |
Meyers A., Trauger S., Webb W., Reisdorph N., Wranik C., Peters E., Siuzdak G.
Protein Profiling with Mass Spectrometry
Spectroscopy, 2003, 17, 1-15
|
| |
| 85 |
Yao S., Meng J., Siuzdak G., Finn M.G.
New Catalysts for Asymmetric Hydrosilylation of Ketones Discovered by Parallel Mass Screening
Journal of Organic Chemistry, 2003, 68, 2540-2546 PDF File
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| 84 |
Trauger S.A., Junker T., Siuzdak G.
Investigating Viral Proteins and Intact Viruses with Mass Spectrometry
Modern Mass Spectrometry, 2003, 225, 265-282
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| |
| 83 |
Go E.P., Prenni J.E., Wei J., Jones A., Hall S.C., Witkowska E., Shen Z., Siuzdak G.
Desorption/Ionization on Silicon Time-of-Flight/Time-of-Flight (DIOS-TOF/TOF) Mass Spectrometry
Anal. Chem., 2003, 75, 2504-2506 PDF File
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| 82 |
Borman S., Russell H., Siuzdak G.
A Mass Spectrometry Timeline
Today's Chemist, 2003, , 47-49 PDF File
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| 81 |
Reisdorph N., Thomas J.J., Katpally U., Chase E., Harris K., Siuzdak G., Smith T.J.
Human Rhinovirus Capsid Dynamics is Controlled by Canyon Flexibility
Virology, 2003, 314, 34-44 PDF File
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| 80 |
Go E.P., Shen Z., Harris K., Siuzdak G.
Quantitative Analysis with Desorption/Ionization on Silicon (DIOS) Mass Spectrometry using Electrospray Deposition
Analytical Chemistry, 2003, 75, 5475-5479 PDF File
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| 79 |
Gentle T., Shen Z., Want E., Siuzdak G., and Others
Diagnosis of Disease using Biomarker Profiles
patent application, 2003, ,
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| 78 |
Sonderegger M., Staniszewski K., Meyers A., Siuzdak G.
A Bioinformatics Approach for Mass Spectrometry Data Processing: Applications to Proteomics and Small Molecule Analysis
Spectroscopy, 2002, 16, 81-87 PDF File
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| 77 |
Shen Z., Yao S., Crowell J., Siuzdak G., Finn M.G.
DIOS-MSEED: A Chip-Based Method for Measurement of Enantiomeric Excess by Kinetic Resolution/Mass Spectrometry
Israel Journal of Chemistry special issue commemorating Wolf Prize to Sharpless, Kagan and Noyori, 2002, 41, 313-316 PDF File
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| 76 |
Grayson M. Editor, Siuzdak G.
Contributor-Biological Mass Spectrometry Measuring Mass: From Positive Rays to Proteins
Chemical Heritage Press, 2002, , 149
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| 75 |
Compton B., Siuzdak G.
Methods for Identifying Compounds from a Sample Matrix
Patent Application, 2002, ,
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| 74 |
Bothner B., Carmitchel L., Staniszewski K., Sonderegger M., Siuzdak G.
Biomolecule Structure Characterization in the Gas Phase using Mass Spectrometry
Spectroscopy, 2002, 16, 71-79 PDF File
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| 73 |
Smith T.J., Schmidt T., Fang J., Wu J., Siuzdak G., Stanley C.
The Structure of Apo Human Glutamate Dehydrogenase Elucidates the Mechanism of Subunit Communication and the Hyerinsulinism/Hyperammonemia Syndrome
Journal of Molecular Biology, 2002, 318, 765-777 PDF File
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| 72 |
Trauger S.A., Webb W., Siuzdak G.
Peptide and Protein Analysis with Mass Spectrometry
Spectroscopy, 2002, 16, 15-28 PDF File
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| |
| 71 |
Thomas J.J., Blackledge R.D., Siuzdak G.
Desorption-Ionization on Silicon Mass Spectrometry: An Application in Forensics
Analytica Chemica Acta, 2001, 442, 183-190 PDF File
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| 70 |
Shen Z., Thomas J.J., Averbuj C., Broo K.M., Engelhard M., Crowell J.E., Finn M.G., Siuzdak G.
Porous Silicon as a Versatile Platform for Laser Desorption/Ionization Mass Spectrometry
Analytical Chemistry, 2001, 33, 179-187 PDF File
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| 69 |
Broo K.M., Wei J., Marshall D., Brown F., Smith T.J., Johnson J.E., Schneemann A., Siuzdak G.
Viral Capsid Mobility: A Dynamic Conduit for Inactivation
Proceedings of the National Academy of Sciences, 2001, 98, 2274-2277 PDF File
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| 68 |
Thomas J.J., Shen Z., Crowell J.E., Finn M.G., Siuzdak G.
Desorption/Ionization on Silicon (DIOS): A Diverse Mass Spectrometry Platform for Protein Characterization
Proceedings of the National Academy of Sciences, 2001, 98, 4932-4937 PDF File
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| 67 |
Bark S.J., Muster N., Yates J.R., Siuzdak G.
High-Temperature Protein Mass Mapping Using a Thermophilic Protease
Journal of the American Chemical Society, 2001, 123, 1774-1775 PDF File
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| 66 |
Fuerstenau S.D., Benner W.H., Thomas J.J., Brugidou C., Bothner B., Siuzdak G.
Mass Spectrometry of an Intact Virus
Angewandte Chemie, 2001, 40, 542-544 PDF File
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| 65 |
Kriwacki R., Siuzdak G.
Probing Protein/Protein Interactions with Mass Spectrometry
Methods in Molecular Biology Humana Press, 2000, , PDF File
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| 64 |
Thomas J.J., Bakhtiar R., Siuzdak G.
Mass Spectrometry in Viral Proteomics
Accounts of Chemical Research, 2000, 33, 179-187 PDF File
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| 63 |
Lewis J.K., Wei J., Siuzdak G.
MALDI Mass Spectrometry in Protein and Peptide Analysis
Encyclopedia of Analytical Chemistry, John Wiley and Sons, NY, 2000, , PDF File
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| 62 |
Bothner B., Chavez R., Wei J., Strupp C., Phung Q., Schneemann A., Siuzdak G.
Monitoring Enzyme Catalysis with Mass Spectrometry
Journal of Biological Chemistry, 2000, 275, 13455-13459 PDF File
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| 61 |
Guo J., Wu J., Siuzdak G., Finn M.G.
Measurement of Enantiomeric Excess by Kinetic Resolution and Mass Spectrometry
Angewandte Chemie Int. Ed., 1999, 38, 1755-1758 PDF File
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| 60 |
Schalley C.A., Rivera J.M., Martin T., Santamaria J., Siuzdak G., Rebek, J. Jr.
Structural Examination of Supramolecular Architectures by Electrospray Ionization Mass Spectrometry
Eur. J. Org. Chem., 1999, , 1325-1331 PDF File
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| 59 |
Schalley C.A., Castellano R.K., Brody M.S., Rudkevich D.M., Siuzdak G., Rebek J.
Investigating Molecular Recognition by Mass Spectrometry: Characterization of Calixarene-Based Self-Assembling Capsule Hosts with Charged Guests
J. Am. Chem. Soc., 1999, 121(19), 4568-4579 PDF File
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| 58 |
Hollenbeck T., Siuzdak G., Blackledge R.D.
Electrospray and MALDI Mass Spectrometry in the Identification of Spermicides in Criminal Investigations
Journal of Forensic Sciences, 1999, 44, 783-788 PDF File
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| 57 |
Takayama S., Chung S.J., Igarashi Y., Ichikawa Y., Sepp A., Lechler R.I., Wu J.Y. Hayashi T., Siuzdak G., Wong C.H.
Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: Donor sugar-nucleotide based approach
Bioorganic & Medicinal Chemistry, 1999, 7, 401-409 PDF File
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| 56 |
Tsui V., Garcia C., Cavagnero S., Siuzdak G., Dyson H.J., Wright P.E.
Quench-Flow Experiments Combined with Mass Spectrometry Show Apomyoglobin Folds through an Obligatory Intermediate
Protein Science, 1999, 8, 45-49 PDF File
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| 55 |
Marmey P., Bothner B., Jacquot E., de Kochko A., Ong C.A., Yot P., Siuzdak G., Beachy R.N., Fauquet C.
Rice Tungro Bacilliform Virus Open Reading Frame 3 Encodes a Single 37-kDa Coat Protein
Virology, 1999, 253, 319-326 PDF File
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| 54 |
Siuzdak G.
Innovations Continue in Mass Spectrometry
Advance, 1999, 8(1), 30-34 PDF File
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| 53 |
Siuzdak G., Hollenbeck T., Bothner B.
Preparative Mass Spectrometry with Electrospray Ionization
Journal of Mass Spectrometry, 1999, 34, 1087-1088 PDF File
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| 52 |
Chatman K.S., Hollenbeck T., Hagey L., Vallee M., Purdy R., Weiss F., Siuzdak G.
Nanoelectrospray Mass Spectrometry and Precursor Ion Monitoring for Quantitative Steroid Analysis and Attomole Sensitivity
Analytical Chemistry, 1999, 71, 2358-2363 PDF File
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| 51 |
Siuzdak G.
Mass Spectrometry
in The Encyclopedia of Molecular Biology T.E. Creighton, Ed., John Wiley & Sons, Inc., New York, NY, 1999, ,
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| 50 |
Bothner B., Schneemann A., Marshall D., Reddy V., Johnson J.E., Siuzdak G.
Crystallographically Identical Virus Capsids Display Different Properties in Solution
Nature Structural Biology, 1999, 6, 114-116 PDF File
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| 49 |
Lewis J.K., Chiang J., Siuzdak G.
Monitoring Protein-Drug Interactions with Mass Spectrometry and Proteolysis Protein Mass Mapping as a Drug Assay
Journal of the Association for Laboratory Automation, 1999, 4, 46-48 PDF File
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| 48 |
Yang C., Gu Z., Yang M., Lin S., Siuzdak G., Smith C.V.
Identification of Modified Tryptophan Residues in Apolipoprotein B-100 Derived from Copper Ion-Oxidized Low-Density Lipoprotein
Biochemistry, 1999, 38, 15903-15908 PDF File
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| 47 |
Wei J., Buriak J., Siuzdak G.
Desorption/Ionization Mass Spectrometry on Porous Silicon
Nature, 1999, 399(6733), 243-246 PDF File
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| 46 |
Siuzdak G., Buriak J., Wei J.
Improved Methods for Laser Desorption from Porous Semiconductors
patent #6, 1999, 288, 390
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| 45 |
Siuzdak G.
Probing Molecular Diversity with Mass Spectrometry
Journal of the Association for Laboratory Automation, 1998, 3(2), 34-37 PDF File
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| 44 |
Niece, R., Siuzdak, G.
Joint ABRF/ASBMB Symposium: Present and Future of Biomolecular Mass Spectrometry
Journal of Biomolecular Techniques, 1998, 9, 22-23
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| 43 |
Owens D.R., Bothner B., Harris K., Phung Q., Siuzdak G.
Aspects of Oligonucleotide and Peptide Sequencing with MALDI and Electrospray Mass Spectrometry
Bioorganic and Medicinal Chemistry, 1998, 6, 1547-1554 PDF File
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| |
| 42 |
Siuzdak G.
Probing Viruses with Mass Spectrometry
Journal of Mass Spectrometry, 1998, 33(3), 203-211 PDF File
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| |
| 41 |
Bothner B., Dong X.F., Bibbs L., Johnson J.E., Siuzdak G.
Evidence of Viral Capsid Dynamics Using Limited Proteolysis and Mass Spectrometry
Journal of Biological Chemistry, 1998, 273(2), 673-676 PDF File
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| |
| 40 |
Siuzdak G., Lewis J.K.
Applications of Mass Spectrometry in Combinatorial Chemistry
Biotechnology & Bioengineering with Combinatorial Chemistry, 1998, 61(2), 127-134 PDF File
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| |
| 39 |
Siuzdak G., Henriksen S.
New Directions in the Analysis of Brain Substances Related to Sleep and Wakefulness
Lydic, R. CRC Press, Methods in the Life Sciences Series; Molecular regulation of arousal states., 1998, , 181-190 PDF File
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| |
| 38 |
Lewis J.K., Bothner B., Smith T.J., Siuzdak G.
Antiviral Agent Blocks Breathing of Common Cold Virus
Proceedings of the National Academy of Sciences, USA, 1998, 95(12), 6774-6778 PDF File
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| 37 |
Lewis J.K., Bendahmane M., Smith T.J., Beachy R.N., Siuzdak G.
Identification of Viral Mutants by Mass Spectrometry
Proceedings of the National Academy of Sciences, USA, 1998, 95, 8596-8601 PDF File
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| |
| 36 |
Kriwacki R., Siuzdak G.
Combined Use of Proteases and Mass Spectrometry in Structural Biology
Journal of Biomolecular Techniques, 1998, 9, 5-15 PDF File
|
| |
| 35 |
Kriwacki R., Wu J., Tennant L., Wright P.E., Siuzdak G.
Probing Protein Structure Using Biochemical and Biophysical Methods: Proteolysis, Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry, High-Performance Liquid Chromatography and Size Exclusion Chromatography of p21graphy of p21Waf1/Cip1/Sdi1
Journal of Chromatography A, 1997, 777, 23-30 PDF File
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| |
| 34 |
Takayama S., Martin R., Wu J., Laslo K., Siuzdak G., Wong C.H.
Chemoenzymatic Preparation of Novel Cyclic Imine Sugars and Rapid Biological Activity Evaluation Using Electrospray Mass Spectrometry and Kinetic Analysis
Journal of the American Chemical Society, 1997, 119(35), 8146-8151 PDF File
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| |
| 33 |
Wu J., Chatman K.S., Harris K., Siuzdak G.
An Automated MALDI Mass Spectrometry Approach for Optimizing Cyclosporin Analysis
Analytical Chemistry, 1997, 69(18), 3767-3771 PDF File
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| |
| 32 |
Wu J., Takayama S., Wong C.H., Siuzdak G.
Quantitative Electrospray Mass Spectrometry for the Rapid Assay of Enzyme Inhibitors
Chemistry & Biology, 1997, 4(9), 653-657 PDF File
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| |
| 31 |
Siuzdak G.
Mass Spectrometry for Biotechnology
Academic Press: San Diego, CA, 1996, , 161
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| |
| 30 |
Fitzgerald M.C., Siuzdak G.
Biochemical Mass Spectrometry: Worth the Weight?
Chemistry and Biology, 1996, 3, 707-715 PDF File
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| |
| 29 |
Kriwacki R., Wu J., Siuzdak G., Wright P.E.
Probing Protein-Protein Interactions by Mass Spectrometry: Analysis of the p21/Cdk2 Complex
Journal of the American Chemical Society, 1996, 118, 5320-5321 PDF File
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| |
| 28 |
Fitzgerald M.C., Harris K., Shevlin C.G., Siuzdak G.
Direct Characterization of Solid Phase Resin-Bound Molecules by Mass Spectrometry
Bioorganic and Medicinal Chemistry Letters, 1996, 6(8), 979-982 PDF File
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| |
| 27 |
Siuzdak G., Bothner B., Yeager M., Brugidou C., Fauquet C.M., Hoey K., Chang C.M.
Mass Spectrometry and Viral Analysis
Chemistry & Biology, 1996, 3, 45 PDF File
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| |
| 26 |
Lerner R.A., Cravatt B., Boger D.L., Siuzdak G. and Henriksen S.
Method for Sleep Induction
international PCT patent application WO 96/09817, 1996, ,
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| |
| 25 |
Chang H.T., Chen C.T., Kondo T., Siuzdak G., and Sharpless K.B.
Asymmetric Dihydroxylation Enables Rapid Construction of Chiral Dendrimers based on 1,2-Diols
Angewandte Chemie, 1996, 35(2), 182-186 PDF File
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| |
| 24 |
Bothner B., Chatman K.S., Sarkisian M., Siuzdak G.
Liquid Chromatography Mass Spectrometry of Antisense Oligonucleotides
Bioorganic and Medicinal Chemistry Letters, 1995, 5(23), 2863-2868 PDF File
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| |
| 23 |
Siuzdak G., Bothner B.
Gas-Phase Micelles
Angewandte Chemie, 1995, 34(18), 2053-2055 PDF File
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| |
| 22 |
Cravatt B., Prospero-Garcia O., Siuzdak G., Gilula N.B., Henriksen S.J., Boger D.L., Lerner R.A.
Chemical Characterization of a Family of Brain Lipids with Sleep Inducing Potential
Science, 1995, 268, 1506-1509 PDF File
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| |
| 21 |
Krebs J.F., Siuzdak G., Dyson H.J., Stewart J.D., Benkovic S.
Detection of a Catalytic Antibody Species Acylated at the Active Site by Electrospray Mass Spectrometry
Biochemistry, 1995, 34, 720-723 PDF File
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| |
| 20 |
Siuzdak G., Zheng Y.L., Ramphal J.Y., Ichikawa Y., Nicolaou K.C., Gaeta F.C.A., Chatman K.S., Wong C.H.
Examination of the Sialyl Lewis X- Calcium Complex by Electrospray Mass Spectrometry
Bioorganic and Medicinal Chemistry Letters, 1994, 4, 2863-2866 PDF File
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| |
| 19 |
Siuzdak G.
The Emergence of Mass Spectrometry in Biochemical Research
Proceedings of the National Academy of Sciences of the United States of America, 1994, 91, 11290-11297 PDF File
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| |
| 18 |
Lerner R.A., Siuzdak G., Prospero-Garcia O., Henriksen S.J., Boger D.L., Cravatt B.
Cerebrodiene: A Brain Lipid Isolated from Sleep-Deprived Cats
Proceedings of the National Academy of Sciences of the United States of America, 1994, 91, 9505-9508
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| |
| 17 |
Stewart J.D., Krebs J.F., Siuzdak G., Berdis A.J., Smithrud D.B., Benkovic S.J.
Dissection of an Antibody-Catalyzed Reaction
Proc. Natl. Acad. Sci., 1994, 91, 7404-7409 PDF File
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| |
| 16 |
Siuzdak G., Krebs J.F., Benkovic S.J., Dyson H.J.
Binding of Hapten to a Single-Chain Catalytic Antibody Demonstrated by Electrospray Mass Spectrometry
Journal of the American Chemical Society, 1994, 116, 7937-7938 PDF File
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| |
| 15 |
Crano J., Knowles D., Kwiatkowski P., Flood T., Ross R., Chiang L., Lasch J., Chadha R., Siuzdak G.
Structure of Three Novel Photochromic Compounds; X-ray Crystallographic and Theoretical Studies
Acta Crystallographica Section B-Structure Science, 1994, 50, 772-779 PDF File
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| |
| 14 |
Rideout D., Bustamante A., Siuzdak G.
Cationic Drug Analysis Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry: Application to Influx Kinetics, Multidrug Resistance and Intracellular Chemical Change
Proceedings of the National Academy of Sciences of the United States of America, 1993, 90(21), 10226-10229 PDF File
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| |
| 13 |
Siuzdak G., Ichikawa Y., Munoz B., Caulfield T.J., Wong C.H., Nicolaou K.C.
Evidence of Calcium-Dependent Carbohydrate Association through Ion Spray Mass Spectrometry
Journal of the American Chemical Society, 1993, 115, 2877-2881 PDF File
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| |
| 12 |
Siuzdak G., Wendeborn S.V., Nicolaou K.C.
Cationization of Organometallo Carbonyl Compounds by Fast Ion Bombardment
Intern. J. of Mass Spectrom. and Ion Proc., 1992, 112, 79-91 PDF File
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| |
| 11 |
BelBruno J.J., Siuzdak G.
Resonant Ionization in Solution: Initiation of ion-molecule chemistry by REMPI
Resonance Ionization Spectroscopy 90, Inst. Phys. Conf. Ser., 1991, 114, 351-354 PDF File
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| |
| 10 |
BelBruno J.J., Siuzdak G.
REMPI-MS: Application to the Study of the Gas Phase Dynamics of Radical Cations
Resonance Ionization Spectroscopy 90, Inst. Phys. Conf. Ser., 1991, 114, 177-180 PDF File
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| |
| 9 |
Siuzdak G., BelBruno J.J.
Multiphoton Ionization of Nitrobenzene in Non-Aqueous Solutions: Characterization of the Cation and Ion-Molecule Chemistry
Laser Chemistry, 1991, 11(2), 83-93 PDF File
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| |
| 8 |
Siuzdak G., North S., BelBruno J.J.
Multiphoton Ionization of Phenol in NonAqueous Solutions: Characterization of the Cation and Ion-Molecule Chemistry
J. Phys. Chem., 1991, 95(13), 5186-5190 PDF File
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| |
| 7 |
BelBruno J.J., Siuzdak G., North S.
Multiphoton-Induced Chemistry of Phenol in Hexane at 266nm
Chem. Phys. Lett., 1990, 166, 167-172 PDF File
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| |
| 6 |
BelBruno J.J., Siuzdak G., North S.
UV Multiphoton Induced Chemistry of Nitrobenzene in Solution
Laser Chemistry, 1990, 10, 177-184 PDF File
|
| |
| 5 |
Siuzdak G., BelBruno J.J.
Multiphoton Ionization Studies of Amines with UV-VIS Lasers
Applied Physics B, 1990, 50, 221-226 PDF File
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| |
| 4 |
Siuzdak G., BelBruno J.J.
Laser Multiphoton Dissociation/Ionization of Butylamines: Competitive Processes in Radical Cations
J. Phys. Chem., 1990, 94(11), 4559-4565 PDF File
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| |
| 3 |
Siuzdak G.
Multiphoton-Induced Chemistry
Ph. D. Thesis University Microfilms International, Dissertation Abstracts International B, 1990, 51(5)2385, 166
|
| |
| 2 |
Marzzacco C.J., Deckey G., Colarulli R., Siuzdak G., Halpern A.
Excited-State Protonation and Photophysical Properties of Azaphenanthrenes
J. Phys. Chem., 1989, 93, 2935-2939 PDF File
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| |
| 1 |
Siuzdak G.
The protonation of 7,8-benzoquinoline in its lowest excited singlet
B.S. Thesis, Rhode Island College,, 1985, ,
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