Welcome to the XCMS Open Source peak picking and nonlinear alignment software homepage!

     XCMS is an LC/MS-based data analysis approach which incorporates novel nonlinear retention time alignment, matched filtration, peak detection, and peak matching.

     XCMS has gained attention in the metabolomics community with its incorporation into GeneSpring MS as well being listed as the most cited 2006 Analytical Chemistry paper.

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Synopsis

     A common goal of all of the metabolomics/proteomics bioinformatic platforms is to allow users to identify and statistically assess metabolite and peptide features that show significant change between sample groups. Recently, XCMS was released as an open source bioinformatics tool to address these goals. XCMS can be distinguished from other programs as it allows for nonlinear spectral alignment and differential analysis as well as being independent of the operating system and distributed under a General Public License. Open source XCMS is written in R which allows it to be highly accessible and modular. The success of XCMS has come from largely achieving the primary goal in identifying and statistically assessing feature metabolite and peptides.