Book Cover
Book Title Activity Metabolomics and Mass Spectrometry
Author Gary Siuzdak
Published MCC Press, San Diego 2024
Keywords Mass Spectrometry, Metabolomics, Metabolite, Metabolism, Ionization, Analyzers, Activity, Discovery
ABSTRACT Mass spectrometry has a special intrigue that comes from its interdisciplinary nature, as it freely crosses the borders of physics, chemistry, and biology. Its history goes back to the early 1900’s, and its development has reached a pinnacle in recent years. Metabolomics and the study of metabolism has also had an equally interesting trajectory encompassing many different technologies; however it is safe to say that mass spectrometry has been a key technology in its evolution. Especially in the realm of Activity Metabolomics and the discovery of biologically active metabolites.
Citation Siuzdak, G., Activity Metabolomics and Mass Spectrometry; MCC Press: San Diego, USA, 2024.
https://doi.org/10.63025/LCUW3037
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Gary Siuzdak, an American chemist, is known for his contributions to the fields of metabolomics, activity metabolomics, and mass spectrometry. Currently, Siuzdak serves as the Professor and Director of The Center for Metabolomics and Mass Spectrometry at Scripps Research in La Jolla, California. He has made significant advancements in virus analysis, viral structural dynamics, and the development of mass spectrometry imaging technology using nanostructured surfaces. The Siuzdak lab is credited with the creation of research tools such as eXtensible Computational Mass Spectrometry (XCMS), METLIN, METLIN Neutral Loss, and Q-MRM. Notably, the XCMS/METLIN platform hosts over 50,000 registered users.